Description
Levocarnitine (L-3-hydroxy-4-N-trimethylaminobutyrate) is synthesized in the liver from the amino acids methionine and lysine. This naturally occurring substance is found in all mammalian tissues, especially striated muscle, and is required in energy metabolism, such as the oxidation of fatty acids, facilitating the aerobic metabolism of carbohydrates, and enhancing the excretion of certain organic acids. While only the L isomer is present in the biologic system, commercial synthesis of carnitine produces a D,L racemic mixture, from which the L-isomer is obtained. The D-isomer has pharmacologic effects but does not participate in lipid metabolism. Commercially, carnitine is available as both a prescription and non-prescription product. The prescription version is levocarnitine, while most dietary supplements contain D,L-carnitine which is commonly sold in health food stores.
Levocarnitine has been used in the treatment of primary and secondary carnitine deficiency in adults and neonates, Alzheimer’s disease, dilated cardiomyopathy in adults and children, valproic acid-induced hepatotoxicity in children, and hyperlipoproteinemia. It has been designated an orphan drug for a variety of conditions. Its use in alcohol induced fatty liver, Down’s syndrome, and chronic fatigue syndrome has shown varying results. Some athletes use carnitine supplements to increase exercise performance, however, the concept of carnitine loading does not appear to be very effective.1 Further, D,L-carnitine competitively inhibits levocarnitine. This inhibition may lead to a deficiency. Prescription forms of levocarnitine were approved by the FDA in 1985 (tablets), 1986 (oral solution), and 1992 (injection)
- Prescription products require an online consultation with a physician who will determine if a prescription is appropriate.
- no products will be shipped until you complete your consultation after purchase, a patient coordinator will contact you within 24 hours to schedule your medical consultation.
- in the event that you are not a candidate, you will be refunded immediately after consultation
- Most medications will arrive 7-10 days after purchase. Please check email once order is complete.
- All products include all needles and supplies for your medication as well as support from our physicians and patient coordinators for time of prescription.
DOSAGE:
L carnitine is taken in a subcutaneous or intramuscular injection. Dosing will be determined by your health care provider during your consultation after purchase.
- Prescription products require an online consultation with a physician who will determine if a prescription is appropriate.
- no products will be shipped until you complete your consultation after purchase, a patient coordinator will contact you within 24 hours to schedule your medical consultation.
- in the event that you are not a candidate, you will be refunded immediately after consultation
- Most medications will arrive 7-10 days after purchase. Please check email once order is complete.
- All products include all needles and supplies for your medication as well as support from our physicians and patient coordinators for time of prescription.
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